(2022-09-18). The thought matrix expands. indybay.org Who has followed the change of the Internet over the last 10 years carefully, will agree with me that the at the beginning very wide spectrum of knowledge, which was available to one in the www, became thinner and thinner and more and more limited. Censorship and deletion of search results is becoming more and more obvious.
(2022-09-17). [Articles] Dupilumab in children aged 6 months to younger than 6 years with uncontrolled atopic dermatitis: a randomised, double-blind, placebo-controlled, phase 3 trial. thelancet.com Dupilumab significantly improved atopic dermatitis signs and symptoms versus placebo in children younger than 6 years. Dupilumab was well tolerated and showed an acceptable safety profile, similar to results in older children and adults.
(2022-09-17). [Comment] Biological therapy for young children with atopic dermatitis. thelancet.com Atopic dermatitis is a common inflammatory skin disease that might lead to severe and persistent disease during infancy. Atopic dermatitis is associated with poor school performance, psychiatric disease, and allergic comorbidities.1—3 If atopic dermatitis is inadequately controlled with emollient use and topical anti-inflammatory therapies, systemic medications including ciclosporin, azathioprine, and methotrexate can be used to treat children with moderate-to-severe disease. However, systemic therapies are rarely used in children because the natural disease course often leads to spontaneous improvement, an…